Two-Domain DNA Strand Displacement

Luca Cardelli
(Microsoft Research)

We investigate the computing power of a restricted class of DNA strand displacement structures: those that are made of double strands with nicks (interruptions) in the top strand. To preserve this structural invariant, we impose restrictions on the single strands they interact with: we consider only two-domain single strands consisting of one toehold domain and one recognition domain. We study fork and join signal-processing gates based on these structures, and we show that these systems are amenable to formalization and to mechanical verification.

In S. Barry Cooper, Prakash Panangaden and Elham Kashefi: Proceedings Sixth Workshop on Developments in Computational Models: Causality, Computation, and Physics (DCM 2010), Edinburgh, Scotland, 9-10th July 2010, Electronic Proceedings in Theoretical Computer Science 26, pp. 47–61.
Published: 9th June 2010.

ArXived at: bibtex PDF

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