Application of a Semi-automatic Algorithm for Identification of Molecular Components in SBML Models

Andrea Maggiolo-Schettini
(Dipartimento di Informatica - Università di Pisa)
Paolo Milazzo
(Dipartimento di Informatica - Università di Pisa)
Giovanni Pardini
(Dipartimento di Informatica - Università di Pisa)

Reactions forming a pathway can be rewritten by making explicit the different molecular components involved in them. A molecular component represents a biological entity (e.g. a protein) in all its states (free, bound, degraded, etc.). In this paper we show the application of a component identification algorithm to a number of real-world models to experimentally validate the approach. Components identification allows subpathways to be computed to better understand the pathway functioning.

In Alex Graudenzi, Giulio Caravagna, Giancarlo Mauri and Marco Antoniotti: Proceedings Wivace 2013 - Italian Workshop on Artificial Life and Evolutionary Computation (Wivace 2013), Milan, Italy, July 1-2, 2013, Electronic Proceedings in Theoretical Computer Science 130, pp. 43–52.
Published: 30th September 2013.

ArXived at: http://dx.doi.org/10.4204/EPTCS.130.7 bibtex PDF
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